Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.69 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758005 | 1.00 | GPR35 (0.69) | GPR35PDK1PDK2PDK3PDK4 | |
| SCHEMBL28923659 | 0.94 | GPR35 (0.61) | GPR35PDK1PDK2PDK3PDK4 | |
| SCHEMBL23466404 | 0.83 | GPR35 (0.53) | GPR35PDK1PDK2PDK3PDK4 | |
| SCHEMBL29758069 | 0.83 | GPR35 (0.53) | GPR35PDK1PDK2PDK3PDK4 | |
| SCHEMBL13170059 | 0.82 | ALDH1A1 (0.54) | GPR35PDK1PDK2PDK3PDK4 | |
| Lodoxamide SCHEMBL119881 | 0.81 | GPR35 (1.00) | GPR35LMNAMAPTTSHRHTT | |
| Lodoxamide SCHEMBL3141058 | 0.80 | GPR35 (0.97) | GPR35LMNAMAPTTSHRHTT | |
| SCHEMBL23486868 | 0.79 | PDK1 (0.46) | GPR35PDK1PDK2PDK3PDK4 | |
| SCHEMBL31703290 | 0.79 | ALDH1A1 (0.55) | GPR35PDK1PDK2PDK3PDK4 | |
| SCHEMBL28974494 | 0.79 | GPR35 (0.49) | GPR35PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169153-A | PROPHYLAXIS, ANTIHISTAMINES | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | claimed |
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| US-4169153-A | PROPHYLAXIS, ANTIHISTAMINES | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4091011-A | PROPHYLACTIC ANTIANAPHYLACTICS, ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1978-05-23 | — | — | US | disclosed |