Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422954 | 0.82 | MAPT (0.48) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL3141077 | 0.79 | CA1 (0.50) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL30686692 | 0.76 | MAPT (0.60) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL5823760 | 0.76 | MAPT (0.60) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL28875589 | 0.74 | MEN1 (0.46) | MAPTRAB9ANPC1LMNAHTT | |
| SCHEMBL17063545 | 0.74 | HPGD (0.59) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL104062 | 0.73 | IDO1 (0.59) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL16961898 | 0.71 | TDP1 (0.60) | MAPTLMNAHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL2204567 | 0.71 | GABRA1 (0.43) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL28426310 | 0.70 | MAPT (0.61) | MAPTRAB9ANPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028521-B | 11-aryl-1, 4-benzoxazinoimidazoline compounds and preparation method and application thereof | 湖南科技大学 | 2020-07-14 | — | — | CN | disclosed |