Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26988922 | 1.00 | P2RX7 (0.35) | P2RX7PDE2ASIRT6GRM2GSK3B | |
| SCHEMBL26988409 | 0.88 | P2RX7 (0.36) | P2RX7PDE2AGRM2GSK3BRXRB | |
| SCHEMBL30722734 | 0.82 | SIRT6 (0.37) | P2RX7SIRT6 | |
| SCHEMBL26988396 | 0.82 | SIRT6 (0.37) | P2RX7SIRT6 | |
| SCHEMBL26988926 | 0.81 | PDE2A (0.37) | P2RX7PDE2AGRM2GSK3BWDR5 | |
| SCHEMBL34470911 | 0.78 | P2RX7 (0.37) | P2RX7PDE2AGRM2GSK3BRXRB | |
| SCHEMBL34470593 | 0.78 | GSK3B (0.38) | P2RX7PDE2AGRM2GSK3BRXRB | |
| SCHEMBL31330662 | 0.78 | P2RX7 (0.37) | P2RX7PDE2AGRM2GSK3BRXRB | |
| SCHEMBL34470460 | 0.77 | GSK3B (0.39) | P2RX7PDE2AGRM2GSK3BRXRB | |
| SCHEMBL31330481 | 0.77 | P2RX7 (0.39) | P2RX7PDE2AGSK3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403806-A | TREM2 modulators | 穆纳治疗有限公司 | 2025-02-07 | — | — | CN | disclosed |