Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26988396 | 1.00 | SIRT6 (0.37) | SIRT6P2RX7OPRK1KCNH2MAPT | |
| SCHEMBL30722815 | 0.90 | P2RX7 (0.33) | P2RX7KCNH2MAPTSPR | |
| SCHEMBL26988872 | 0.90 | P2RX7 (0.33) | P2RX7KCNH2MAPTSPR | |
| SCHEMBL26988922 | 0.82 | P2RX7 (0.35) | SIRT6P2RX7 | |
| SCHEMBL31411026 | 0.82 | P2RX7 (0.35) | SIRT6P2RX7 | |
| SCHEMBL31360909 | 0.78 | POLB (0.34) | P2RX7KCNH2MAPT | |
| SCHEMBL26988409 | 0.72 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL31360827 | 0.70 | CHRNB2 (0.34) | P2RX7 | |
| SCHEMBL34470856 | 0.69 | P2RX7 (0.36) | P2RX7OPRK1SPR | |
| SCHEMBL34470524 | 0.69 | P2RX7 (0.37) | P2RX7SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551575-A2 | TREM2 MODULATORS | Muna Therapeutics ApS (DK) | 2025-05-14 | — | — | EP | disclosed |
| CN-119403806-A | TREM2 modulators | 穆纳治疗有限公司 | 2025-02-07 | — | — | CN | disclosed |
| WO-2024008722-A2 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2024-01-11 | — | — | WO | disclosed |