Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LSS | P48449 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120763 | 1.00 | DGAT1 (0.43) | DGAT1KDM4ELSSFPR2NPC1 | |
| SCHEMBL22907011 | 1.00 | DGAT1 (0.43) | DGAT1KDM4ELSSFPR2NPC1 | |
| SCHEMBL30556450 | 0.99 | DGAT1 (0.43) | DGAT1KDM4ELSSFPR2NPC1 | |
| SCHEMBL31274495 | 0.99 | DGAT1 (0.43) | DGAT1KDM4ELSSFPR2NPC1 | |
| SCHEMBL17941145 | 0.90 | DGAT1 (0.43) | DGAT1KDM4ELSSFPR2NPC1 | |
| SCHEMBL23348624 | 0.86 | KDM4E (0.50) | DGAT1KDM4EFPR2NPC1RECQL | |
| SCHEMBL23720486 | 0.81 | BCHE (0.43) | DGAT1KDM4EFPR2NPC1RECQL | |
| SCHEMBL31108106 | 0.81 | CCNB2 (0.34) | DGAT1KDM4EFPR2ALDH1A1LATS1 | |
| SCHEMBL25259501 | 0.81 | FPR2 (0.35) | KDM4EFPR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21405025 | 0.81 | FPR2 (0.35) | KDM4EFPR2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |