SCHEMBL25259501

SCHEMBL25259501

CC(C)(C)OC(=O)COCCOCCOCCOCCOc1cc(Br)ccn1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.35
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
AAK1 Q2M2I8 4/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
NPC1 O15118 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
LATS1 O95835 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SSTR4 P31391 1/20 0.32
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29838235 1.00 FPR2 (0.35) FPR2ALDH1A1KDM4ESMN1; SMN2AAK1
SCHEMBL21405025 1.00 FPR2 (0.35) FPR2ALDH1A1KDM4ESMN1; SMN2AAK1
SCHEMBL31402216 1.00 FPR2 (0.35) FPR2ALDH1A1KDM4ESMN1; SMN2AAK1
SCHEMBL18551716 0.99 FPR2 (0.36) FPR2ALDH1A1KDM4ESMN1; SMN2AAK1
SCHEMBL31370820 0.87 ALDH1A1 (0.39) FPR2ALDH1A1KDM4ESMN1; SMN2AAK1
SCHEMBL21405217 0.86 KDM4E (0.36) ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A
SCHEMBL29838308 0.86 KDM4E (0.36) ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A
SCHEMBL31402275 0.82 BCHE (0.45) KDM4EAAK1
SCHEMBL31402257 0.82 BCHE (0.45) KDM4EAAK1
SCHEMBL31402250 0.82 BCHE (0.45) KDM4EAAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-03-06 US disclosed
EP-4452966-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2024-10-30 EP disclosed
WO-2023115149-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS MLKL, RIPK3, CASP9 FPR2 2043/4885ALDH1A1 4680/4885KDM4E 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.