SCHEMBL31411331

SCHEMBL31411331

Fc1ccc2[nH]nc(I)c2c1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
PDPK1 O15530 1/20 0.35
HTR2A P28223 2/20 0.33
HTR6 P50406 2/20 0.33
HTR7 P34969 1/20 0.31
GRM4 Q14833 1/20 0.30
DAPK3 O43293 1/20 0.30
PRKD3 O94806 1/20 0.30
MAP4K4 O95819 1/20 0.30
PAK4 O96013 1/20 0.30
ABL1 P00519 1/20 0.30
NTRK1 P04629 1/20 0.30
LCK P06239 1/20 0.30
CSF1R P07333 1/20 0.30
RET P07949 1/20 0.30
IGF1R P08069 1/20 0.30
MET P08581 1/20 0.30
PDGFRB P09619 1/20 0.30
FGFR1 P11362 1/20 0.30
PRKACA P17612 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14631528 0.81 GRM4 (0.35) PDPK1GRM4DAO
SCHEMBL14631436 0.81 GAA (0.37) PDPK1HTR6HTR7GRM4
SCHEMBL20764903 0.81 HTR1A (0.35) PDPK1HTR6HTR7
SCHEMBL4152331 0.77 MAP2K1 (0.41) PDPK1GRM4MAP2K1LRRK2
SCHEMBL31411486 0.77 HTR1A (0.40) HTR2AHTR6HTR7GRM4NTRK1
SCHEMBL31411291 0.77 GRM4 (0.33) PDPK1GRM4
SCHEMBL18552944 0.76 GPR84 (0.39) GPR84HTR2AHTR6HTR7GRM4
SCHEMBL12325104 0.76 KDR (0.47) GPR84PDPK1DAPK3PRKD3MAP4K4
SCHEMBL5952759 0.76 PDPK1 (0.47) GPR84PDPK1HTR2ADAPK3PRKD3
SCHEMBL31411285 0.72 GPR84 (0.36) GPR84HTR2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB GPR84 3280/4885PDPK1 1912/4885HTR2A 94/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB GPR84 3280/4885PDPK1 1912/4885HTR2A 94/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB GPR84 3280/4885PDPK1 1912/4885HTR2A 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.