SCHEMBL31411441

SCHEMBL31411441

COc1ccc2c(c(CCO)nn2COCC[Si](C)(C)C)c1F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.33
F2RL1 P55085 1/20 0.32
EGFR P00533 1/20 0.30
IGF1R P08069 1/20 0.30
SRC P12931 1/20 0.30
FLT4 P35916 1/20 0.30
KDR P35968 1/20 0.30
FLT3 P36888 1/20 0.30
EPHB4 P54760 1/20 0.30
TEK Q02763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411472 0.87 HTR1A (0.40) DGAT1
SCHEMBL31411473 0.87 HTR1A (0.40) DGAT1
SCHEMBL31411481 0.87 EGFR (0.31) DGAT1F2RL1EGFRIGF1RSRC
SCHEMBL31411402 0.85 F2RL1 (0.35) DGAT1F2RL1EGFRIGF1RSRC
SCHEMBL31411459 0.85 HTR1A (0.32) DGAT1
SCHEMBL31411329 0.84 HTR1A (0.31) DGAT1
SCHEMBL31411474 0.83 DGAT1 (0.35) DGAT1EGFRIGF1RSRCFLT4
SCHEMBL31411283 0.83 F2RL1 (0.35) DGAT1F2RL1
SCHEMBL31411292 0.82 DGAT1 (0.35) DGAT1F2RL1
SCHEMBL31411270 0.81 NPC1 (0.35) DGAT1F2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB DGAT1 1102/4885F2RL1 4296/4885EGFR 2960/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB DGAT1 1102/4885F2RL1 4296/4885EGFR 2960/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB DGAT1 1102/4885F2RL1 4296/4885EGFR 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.