SCHEMBL31411445

SCHEMBL31411445

COc1cc2c(CCO)n[nH]c2cc1F

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HTR1A P08908 1/20 0.42
▸ HTR2B P41595 1/20 0.41
▸ MTNR1A P48039 2/20 0.39
▸ LMNA P02545 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ MAPK10 P53779 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ MTNR1B P49286 1/20 0.37
▸ LRRK2 Q5S007 7/20 0.37
▸ ILK Q13418 1/20 0.35
▸ NCOA1 Q15788 1/20 0.35
▸ NCOA3 Q9Y6Q9 1/20 0.35
▸ MAPK1 P28482 3/20 0.33
▸ GRM4 Q14833 1/20 0.33
▸ MAP2K4 P45985 1/20 0.33
▸ MAPKAPK2 P49137 1/20 0.33
▸ MAPKAPK3 Q16644 1/20 0.33
▸ MAPK6 Q16659 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411338 0.83 HTR1A (0.59) HTR1AHTR2BMTNR1ALMNARAB9A
SCHEMBL31411383 0.80 HTR1A (0.46) HTR1AHTR2BMTNR1ALMNARAB9A
SCHEMBL31411448 0.79 HTR1A (0.40) HTR1AHTR2BLMNASMN1; SMN2HSD17B10
SCHEMBL31411350 0.79 HTR1A (0.45) HTR1AHTR2BMTNR1ALMNARAB9A
SCHEMBL31651554 0.79 HTR1A (0.42) HTR1AHTR2BHSD17B10LRRK2
SCHEMBL31411320 0.77 HTR1A (0.44) HTR1AHTR2BMTNR1ALMNARAB9A
SCHEMBL31411485 0.77 LRRK2 (0.37) HTR1AHTR2BMTNR1AMTNR1BLRRK2
SCHEMBL31411491 0.76 HTR1A (0.36) HTR1AHTR2BMTNR1ALMNARAB9A
SCHEMBL31411298 0.76 HRH3 (0.38) HTR1AMTNR1AMTNR1BLRRK2
SCHEMBL31411417 0.74 HTR1A (0.40) HTR1AHTR2BMTNR1ALMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885HTR2B 114/4885MTNR1A 888/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885HTR2B 114/4885MTNR1A 888/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885HTR2B 114/4885MTNR1A 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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