SCHEMBL31411491

SCHEMBL31411491

COc1cc2c(CCN3CC4CC4C3)n[nH]c2cc1F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ HTR1A P08908 1/20 0.36
▸ LRRK2 Q5S007 15/20 0.35
▸ MTNR1A P48039 1/20 0.34
▸ MTNR1B P49286 1/20 0.34
▸ FPR2 P25090 1/20 0.34
▸ PROKR1 Q8TCW9 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ MAPK10 P53779 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL31651561 0.91 MTNR1A (0.36) LRRK2MTNR1AMTNR1BFPR2PROKR1
SCHEMBL31411485 0.90 LRRK2 (0.37) HTR1ALRRK2MTNR1AMTNR1BHTR2B
SCHEMBL31411448 0.85 HTR1A (0.40) HTR1ALRRK2LMNASMN1; SMN2HSD17B10
SCHEMBL31651554 0.85 HTR1A (0.42) HTR1ALRRK2HSD17B10HTR2B
Fumaric Acid SCHEMBL31411289 0.81 ESR1 (0.37) LRRK2MTNR1AMTNR1BLMNARAB9A
SCHEMBL31411469 0.81 MTNR1A (0.34) HTR1ALRRK2MTNR1AMTNR1BFPR2
SCHEMBL31411298 0.79 HRH3 (0.38) HTR1ALRRK2MTNR1AMTNR1B
Fumaric Acid SCHEMBL31411274 0.77 ACHE (0.37) HTR1ALRRK2MTNR1AMTNR1BLMNA
SCHEMBL31411445 0.76 HTR1A (0.42) HTR1ALRRK2MTNR1AMTNR1BLMNA
SCHEMBL31411338 0.74 HTR1A (0.59) HTR1AMTNR1AMTNR1BLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885LRRK2 1294/4885MTNR1A 888/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885LRRK2 1294/4885MTNR1A 888/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885LRRK2 1294/4885MTNR1A 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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