Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411885 | 0.93 | HPGD (0.60) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL31411783 | 0.88 | ALDH1A1 (0.57) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL23768992 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNASMN1; SMN2CYP2C9 | |
| SCHEMBL29978848 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNASMN1; SMN2CYP2C9 | |
| SCHEMBL31411784 | 0.81 | ALDH1A1 (0.56) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL31411774 | 0.81 | ALDH1A1 (0.56) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL31411689 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL31411673 | 0.79 | MAPT (0.53) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL31411550 | 0.79 | LMNA (0.58) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL4014992 | 0.77 | CMA1 (0.66) | HPGDALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |