Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411590 | 0.95 | MAPT (0.45) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411677 | 0.87 | MAPT (0.57) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411719 | 0.86 | MAPT (0.50) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411622 | 0.85 | DHPS (0.35) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411828 | 0.85 | MAPT (0.59) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411765 | 0.84 | MAPT (0.56) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411735 | 0.82 | ALDH1A1 (0.52) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411687 | 0.81 | MAPT (0.38) | MAPTLMNAALDH1A1TP53 | |
| SCHEMBL31411674 | 0.80 | MAPT (0.50) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31411673 | 0.79 | MAPT (0.53) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |