Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411872 | 1.00 | CHRNA4 (0.40) | CHRNA4CHRNB2CHRNA7NPC1RAB9A | |
| SCHEMBL14108403 | 0.83 | MLLT1 (0.47) | CHRNA4CHRNB2CHRNA7NPC1RAB9A | |
| SCHEMBL31411883 | 0.83 | CHRNA4 (0.40) | CHRNA4CHRNB2CHRNA7SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28847292 | 0.82 | MLLT1 (0.46) | CHRNA4CHRNB2CHRNA7NPC1RAB9A | |
| SCHEMBL25213670 | 0.81 | NPC1 (0.54) | NPC1RAB9ATDP1TSHRSMN1; SMN2 | |
| SCHEMBL30436829 | 0.80 | GABRA1 (0.39) | CHRNA4CHRNB2CHRNA7NPC1RAB9A | |
| SCHEMBL30424616 | 0.79 | NPC1 (0.56) | NPC1RAB9ATDP1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL693291 | 0.76 | SMYD3 (0.59) | CHRNA4NPC1RAB9AS1PR1 | |
| SCHEMBL3367312 | 0.76 | NPC1 (0.43) | CHRNA4CHRNB2CHRNA7NPC1RAB9A | |
| SCHEMBL31411850 | 0.76 | CD38 (0.43) | CHRNA4CHRNB2CHRNA7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | claimed |