Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411804 | 0.83 | CHRNA4 (0.40) | CHRNA4CHRNB2CHRNA7SMN1; SMN2 | |
| SCHEMBL31411872 | 0.83 | CHRNA4 (0.40) | CHRNA4CHRNB2CHRNA7SMN1; SMN2 | |
| SCHEMBL14108403 | 0.78 | MLLT1 (0.47) | CHRNA4CHRNB2CHRNA7SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28847292 | 0.77 | MLLT1 (0.46) | CHRNA4CHRNB2CHRNA7SMN1; SMN2 | |
| SCHEMBL30436829 | 0.75 | GABRA1 (0.39) | CHRNA4CHRNB2CHRNA7EPHX2GAA | |
| SCHEMBL30424616 | 0.74 | NPC1 (0.56) | SMN1; SMN2 | |
| SCHEMBL27028220 | 0.73 | CNR2 (0.47) | CHRNA4CHRNB2CHRNA7SMN1; SMN2 | |
| SCHEMBL289997 | 0.71 | — | — | |
| SCHEMBL31411850 | 0.71 | CD38 (0.43) | CHRNA4CHRNB2CHRNA7SMN1; SMN2 | |
| SCHEMBL3367312 | 0.71 | NPC1 (0.43) | CHRNA4CHRNB2CHRNA7GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | claimed |