Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339344 | 0.93 | TSHR (0.49) | TSHRHSD17B10KDM4EMAPK1LCK | |
| SCHEMBL30575711 | 0.92 | TSHR (0.43) | TSHRHSD17B10KDM4EMAPK1LCK | |
| SCHEMBL14914576 | 0.87 | TSHR (0.47) | TSHRHSD17B10KDM4EMAPK1LCK | |
| SCHEMBL14914573 | 0.82 | LCK (0.51) | TSHRHSD17B10KDM4EMAPK1LCK | |
| SCHEMBL14915377 | 0.78 | ALDH1A1 (0.47) | TSHRHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL12245587 | 0.76 | LCK (0.55) | TSHRHSD17B10KDM4EMAPK1LCK | |
| SCHEMBL31609523 | 0.74 | DPP4 (0.42) | KDM4EKMT2AMEN1MAPTKDM1A | |
| SCHEMBL24257971 | 0.73 | SMN1; SMN2 (0.48) | TSHRHSD17B10KDM4EMAPK1MAPT | |
| SCHEMBL30575774 | 0.73 | SMN1; SMN2 (0.48) | TSHRHSD17B10KDM4EMAPK1MAPT | |
| SCHEMBL5240208 | 0.71 | LCK (0.53) | TSHRKDM4EMAPK1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403800-A | Compounds and their use as LPAR5 antagonists | 艾美斐生物医药科技(上海)有限公司 | 2025-02-07 | — | — | CN | disclosed |