Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143789 | 1.00 | HTT (0.41) | HTTALOX15PDE4BSUV39H2KDM4E | |
| SCHEMBL4480745 | 0.81 | SPR (0.43) | SUV39H2KDM4EL3MBTL1BTKKMT2A | |
| SCHEMBL2945528 | 0.78 | IKBKE (0.41) | ALOX15SUV39H2KDM4EALDH1A1IKBKE | |
| SCHEMBL27359300 | 0.76 | BTK (0.40) | SUV39H2IKBKETBK1BTKKMT2A | |
| SCHEMBL31413455 | 0.75 | ALOX15 (0.43) | HTTALOX15PDE4BKDM4EALDH1A1 | |
| SCHEMBL27138635 | 0.75 | ALOX15 (0.43) | HTTALOX15PDE4BKDM4EALDH1A1 | |
| SCHEMBL25190263 | 0.75 | RAB9A (0.41) | ALOX15SUV39H2KDM4EALDH1A1LMNA | |
| SCHEMBL31413412 | 0.72 | HTT (0.47) | HTTALOX15PDE4BKDM4EALDH1A1 | |
| SCHEMBL27140082 | 0.72 | HTT (0.47) | HTTALOX15PDE4BKDM4EALDH1A1 | |
| SCHEMBL31413381 | 0.69 | HTT (0.43) | HTTALOX15PDE4BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |