Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20257060 | 0.85 | MAP2K4 (0.40) | GRIN2DGRIN1GRIN2AGRIN2BGRIN2C | |
| SCHEMBL31414547 | 0.83 | GABRA1 (0.42) | NUDT1GRIN2DGRIN1GRIN2AGRIN2B | |
| SCHEMBL31414560 | 0.83 | TNKS2 (0.43) | NUDT1GRIN2DGRIN1GRIN2AGRIN2B | |
| SCHEMBL31414582 | 0.83 | PARP1 (0.46) | NUDT1GRIN2DGRIN1GRIN2AGRIN2B | |
| SCHEMBL15131384 | 0.82 | RXRA (0.42) | GRIN2DGRIN1GRIN2AGRIN2BGRIN2C | |
| SCHEMBL31414594 | 0.79 | HRH3 (0.57) | ALOX15MEN1KMT2ANPC1POLB | |
| SCHEMBL2761945 | 0.77 | KDM4E (0.49) | GRIN2DGRIN1GRIN2AGRIN2BGRIN2C | |
| SCHEMBL31414494 | 0.76 | MLYCD (0.55) | MEN1KMT2ARAB9A | |
| SCHEMBL2001667 | 0.76 | KDM4E (0.58) | GRIN2DGRIN1GRIN2AGRIN2BGRIN2C | |
| SCHEMBL30147598 | 0.75 | FLT3 (0.55) | NUDT1ALOX15MEN1KMT2ARCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735422-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | Sanofi (FR) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006827-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | GENZYME CORPORATION (US) | 2025-01-02 | — | — | WO | disclosed |