Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL6657504 | 0.98 | CA4 (0.85) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28145127 | 0.98 | CA4 (0.85) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL5557290 | 0.98 | CA4 (0.85) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28131934 | 0.95 | CA4 (0.80) | CA4ALDH1A1 | |
| Citric Acid SCHEMBL8065018 | 0.95 | CA4 (0.90) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL852449 | 0.95 | CA4 (0.90) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29802314 | 0.95 | CA4 (0.90) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL710052 | 0.93 | CA4 (0.85) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28068545 | 0.93 | CA4 (0.85) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL9780898 | 0.93 | CA4 (0.85) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119639537-A | Fermented green plum wine and preparation method thereof | 广东顺德酒厂有限公司 | 2025-03-18 | — | — | CN | disclosed |