Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415764 | 0.81 | CYP11B1 (0.55) | TBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL31415759 | 0.79 | CYP19A1 (0.64) | TBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL31415789 | 0.79 | CYP11B1 (0.52) | TBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL31415765 | 0.79 | SMN1; SMN2 (0.56) | KMT2AKDM4EALDH1A1CYP19A1MEN1 | |
| SCHEMBL31415754 | 0.79 | CYP19A1 (0.62) | TBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL10370478 | 0.78 | TBXAS1 (1.00) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL31415749 | 0.78 | CYP11B1 (0.51) | TBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL31415793 | 0.78 | CYP19A1 (0.48) | TBXAS1LTA4HCYP19A1 | |
| Hydrochloric Acid SCHEMBL9996050 | 0.77 | TBXAS1 (0.97) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL31415787 | 0.76 | CYP19A1 (0.50) | TBXAS1CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | claimed |
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | disclosed |