Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986508 | 0.88 | TDP1 (0.34) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL25949117 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LIMK1LIMK2 | |
| SCHEMBL30986355 | 0.77 | TDP1 (0.36) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL25318850 | 0.76 | TUBB4A (0.40) | TDP1L3MBTL1ALDH1A1LIMK1LIMK2 | |
| SCHEMBL30508801 | 0.76 | TUBB4A (0.40) | TDP1L3MBTL1ALDH1A1LIMK1LIMK2 | |
| SCHEMBL25317896 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL31416832 | 0.71 | KDM4E (0.32) | — | |
| SCHEMBL31361106 | 0.69 | ALDH1A1 (0.40) | TDP1L3MBTL1ALDH1A1LIMK1LIMK2 | |
| SCHEMBL31361239 | 0.68 | PTGS2 (0.33) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL31078187 | 0.68 | RPS6KA5 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |