Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | LIPC | P11150 | 3/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416814 | 0.84 | KMT2A (0.44) | ALDH1A1HTTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL31416745 | 0.69 | PIK3CD (0.36) | PDE10AALDH1A1HTTPIK3CAPI4KA | |
| SCHEMBL31416730 | 0.68 | PIK3CD (0.45) | PDE10AALDH1A1PIK3CAPI4KAPIK3CG | |
| SCHEMBL34469724 | 0.66 | KDM4E (0.40) | MAPTPDE10AALDH1A1PIK3CAPI4KA | |
| SCHEMBL23617959 | 0.65 | CYP2C19 (0.45) | ADORA2APDE10AALDH1A1HDAC6CYP2C9 | |
| SCHEMBL7229990 | 0.64 | RIPK1 (0.34) | MAPTALDH1A1HTTPI4KBLMNA | |
| SCHEMBL31416779 | 0.64 | PIK3CD (0.34) | PDE10APIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL34470098 | 0.64 | GAA (0.40) | MAPTPDE10AALDH1A1HTTHDAC6 | |
| SCHEMBL18631035 | 0.63 | KMO (0.47) | HDAC6LMNACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL34469948 | 0.63 | PDE10A (0.38) | PDE10APIK3CAPI4KAPIK3CGPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |