Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | PI4KA | P42356 | 3/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | RORB | Q92753 | 13/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416745 | 0.88 | PIK3CD (0.36) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG | |
| SCHEMBL31416814 | 0.83 | KMT2A (0.44) | ALDH1A1RORC | |
| SCHEMBL31416726 | 0.74 | LRRK2 (0.38) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG | |
| SCHEMBL31416779 | 0.71 | PIK3CD (0.34) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG | |
| SCHEMBL34469948 | 0.70 | PDE10A (0.38) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG | |
| SCHEMBL31416713 | 0.68 | ADORA3 (0.36) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG | |
| SCHEMBL330400 | 0.68 | ALDH1A1 (0.65) | RORBALDH1A1HSD17B10 | |
| SCHEMBL34469724 | 0.67 | KDM4E (0.40) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG | |
| SCHEMBL7952618 | 0.66 | SMN1; SMN2 (0.42) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG | |
| SCHEMBL1256374 | 0.66 | ALDH1A1 (0.54) | PIK3CDPIK3CAPI4KAPI4KBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |