Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632138 | 0.80 | ALDH1A1 (0.44) | MAPTALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL24062854 | 0.77 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL7230088 | 0.75 | POLB (0.34) | MAPTALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL25296431 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL4319999 | 0.71 | MAPT (0.55) | MAPTALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL3823010 | 0.68 | RAB9A (0.44) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL860102 | 0.68 | — | — | |
| SCHEMBL25191991 | 0.67 | FBP1 (0.50) | MAPTALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL16636659 | 0.67 | MEN1 (0.36) | MAPTALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL9501995 | 0.67 | PTGDR2 (0.41) | MAPTALDH1A1PTGDR2SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |