Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31417692 | 0.90 | KDM4E (0.37) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD | |
| SCHEMBL31417790 | 0.88 | KDM4E (0.36) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD | |
| SCHEMBL31417732 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1SOS1HPGDHSD17B10 | |
| SCHEMBL31417577 | 0.81 | SOS1 (0.46) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD | |
| SCHEMBL14126349 | 0.81 | ALDH1A1 (0.38) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD | |
| SCHEMBL31417774 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD | |
| SCHEMBL31417569 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD | |
| SCHEMBL31417527 | 0.78 | ACHE (0.36) | KDM4EALDH1A1SOS1HPGDHSD17B10 | |
| SCHEMBL23698351 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD | |
| SCHEMBL19126021 | 0.77 | ALDH1A1 (0.39) | KDM4EALDH1A1SOS1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016457-A1 | NEW SUBSTITUTED HETEROCYCLIC COMPOUND AS GSPTS/MYC SIGNAL FLUX REGULATOR | 杭州德睿智药科技有限公司 | 2025-01-23 | — | — | WO | disclosed |