Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29739447 | 0.88 | DHODH (0.47) | NPC1RAB9AMAPTSMN1; SMN2KDR | |
| SCHEMBL31135377 | 0.87 | BRAF (0.47) | NPC1RAB9AMAPTSMN1; SMN2KDR | |
| SCHEMBL1984984 | 0.86 | SMN1; SMN2 (0.49) | NPC1RAB9AMAPTSMN1; SMN2KDR | |
| SCHEMBL27352139 | 0.84 | EPHX2 (0.47) | NPC1RAB9AMAPTSMN1; SMN2KDR | |
| SCHEMBL31417741 | 0.84 | EPHX2 (0.47) | NPC1RAB9AMAPTSMN1; SMN2KDR | |
| SCHEMBL9615374 | 0.84 | RAB9A (0.58) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL16907381 | 0.83 | RAB9A (0.56) | NPC1RAB9AMAPTKDRHPGD | |
| SCHEMBL31158631 | 0.78 | GAA (0.50) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL3257836 | 0.77 | HPGD (0.42) | NPC1RAB9ASMN1; SMN2EPHX2HPGD | |
| SCHEMBL20707888 | 0.77 | RIPK1 (0.53) | KDRBRAFEPHX2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016457-A1 | NEW SUBSTITUTED HETEROCYCLIC COMPOUND AS GSPTS/MYC SIGNAL FLUX REGULATOR | 杭州德睿智药科技有限公司 | 2025-01-23 | — | — | WO | disclosed |