Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15651553 | 0.82 | RAB9A (0.49) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL2867522 | 0.77 | NFKB1 (0.55) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL569698 | 0.77 | ECE1 (0.56) | RAB9AMAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL3061177 | 0.76 | RAB9A (0.52) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL2866116 | 0.76 | LMNA (0.53) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11723024 | 0.75 | MAPT (0.57) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL3150658 | 0.75 | EPHX1 (0.53) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL2868228 | 0.75 | NPC1 (0.49) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL3145142 | 0.73 | RAB9A (0.45) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL4366823 | 0.73 | MAPT (0.50) | RAB9AMAPTKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747196-B1 | SUBSTITUTED ARYL ACYLTHIOUREAS AND RELATED COMPOUNDS; INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS INC (US) | 2010-02-10 | — | — | EP | disclosed |