Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17108416 | 0.89 | MPO (0.59) | MPOCYP1A2CYP2D6BCL2CYP19A1 | |
| SCHEMBL13133328 | 0.82 | KDM4E (0.44) | MPOCYP1A2CYP2D6BCL2CYP19A1 | |
| SCHEMBL16313341 | 0.82 | KDM4E (0.54) | MPOCYP1A2CYP2D6BCL2CYP19A1 | |
| SCHEMBL11786798 | 0.81 | METAP1 (0.48) | CYP1A2CYP2D6CYP19A1KDM4EMAPT | |
| SCHEMBL11471048 | 0.80 | METAP1 (0.59) | MPOCYP1A2CYP2D6BCL2CYP19A1 | |
| SCHEMBL15869785 | 0.80 | MPO (0.51) | MPOCYP1A2CYP2D6BCL2CYP19A1 | |
| SCHEMBL268592 | 0.80 | KDM4E (0.56) | MPOCYP1A2CYP2D6CYP19A1KDM4E | |
| SCHEMBL8174050 | 0.79 | SRD5A1 (0.63) | CYP1A2CYP19A1CYP11B2MAPTALDH1A1 | |
| SCHEMBL23142694 | 0.79 | MIF (0.54) | MPOCYP1A2CYP2D6CYP19A1KDM4E | |
| SCHEMBL7284296 | 0.79 | ALDH1A1 (0.55) | MPOCYP1A2CYP2D6BCL2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642380-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-01-05 | — | — | US | disclosed |
| CN-101395127-A | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO (JP) | 2009-03-25 | — | — | CN | disclosed |
| US-20070236137-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070236137-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | TYR, MAOA, MAOB | MPO 615/4885CYP1A2 289/4885CYP2D6 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.