Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420279 | 0.88 | USP30 (0.45) | USP30SCD5PTPN2PTPN1PTPN6 | |
| SCHEMBL31420237 | 0.87 | NPC1 (0.52) | USP30SCD5PTPN2PTPN1PTPN6 | |
| SCHEMBL31420249 | 0.87 | NPC1 (0.52) | USP30SCD5PTPN2PTPN1PTPN6 | |
| SCHEMBL31420235 | 0.81 | UCHL1 (0.50) | USP30NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL30718466 | 0.80 | GPR119 (0.44) | USP30PTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL31420261 | 0.80 | PTPN2 (0.48) | USP30PTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL27311841 | 0.77 | L3MBTL1 (0.53) | USP30PTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL30247993 | 0.76 | L3MBTL1 (0.55) | USP30PTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL23389450 | 0.73 | CLK1 (0.49) | USP30PTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL29919379 | 0.73 | CLK1 (0.49) | USP30PTPN2PTPN1PTPN6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528901-B | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | Shanghai tongji hospital (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119528901-A | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | 上海市同济医院 | 2025-02-28 | — | — | CN | disclosed |