Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420245 | 1.00 | DYRK1A (0.51) | DYRK1AL3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL30248371 | 0.93 | L3MBTL1 (0.57) | DYRK1AL3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL30248235 | 0.93 | L3MBTL1 (0.57) | DYRK1AL3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL27311609 | 0.93 | L3MBTL1 (0.57) | DYRK1AL3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL27311841 | 0.86 | L3MBTL1 (0.53) | L3MBTL1PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL27310295 | 0.84 | RAB9A (0.56) | DYRK1AL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL31420237 | 0.83 | NPC1 (0.52) | L3MBTL1PTPN2PTPN1PTPN6ADORA1 | |
| SCHEMBL31420221 | 0.83 | PTPN2 (0.46) | L3MBTL1PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL30247902 | 0.82 | L3MBTL1 (0.56) | L3MBTL1PTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL31420255 | 0.82 | ABL1 (0.48) | L3MBTL1PTPN2PTPN1PTPN6USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528901-B | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | Shanghai tongji hospital (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119528901-A | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | 上海市同济医院 | 2025-02-28 | — | — | CN | disclosed |