Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420310 | 1.00 | ABL1 (0.48) | ABL1L3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL31420224 | 0.94 | L3MBTL1 (0.52) | ABL1L3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL30718471 | 0.87 | GPR119 (0.49) | ABL1L3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL31420221 | 0.83 | PTPN2 (0.46) | ABL1L3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL31420246 | 0.82 | DYRK1A (0.51) | ABL1L3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL31420245 | 0.82 | DYRK1A (0.51) | ABL1L3MBTL1PTPN2PTPN1PTPN6 | |
| SCHEMBL31420237 | 0.82 | NPC1 (0.52) | L3MBTL1PTPN2PTPN1PTPN6ADORA2A | |
| SCHEMBL31420241 | 0.82 | UCHL1 (0.47) | ABL1ADORA2AROCK2MAP4K1USP30 | |
| SCHEMBL31420247 | 0.82 | UCHL1 (0.47) | ABL1ADORA2AROCK2MAP4K1USP30 | |
| SCHEMBL27311841 | 0.80 | L3MBTL1 (0.53) | L3MBTL1PTPN2PTPN1PTPN6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528901-B | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | Shanghai tongji hospital (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119528901-A | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | 上海市同济医院 | 2025-02-28 | — | — | CN | disclosed |