SCHEMBL31420909

SCHEMBL31420909

CC(C)OCCNCCNC(=O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HTT P42858 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPT P10636 1/20 0.52
SLC1A3 P43003 1/20 0.51
SLC1A1 P43005 1/20 0.51
ATM Q13315 1/20 0.48
TGM2 P21980 1/20 0.48
KEAP1 Q14145 2/20 0.47
NFE2L2 Q16236 2/20 0.47
CTSK P43235 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22984652 0.86 HTT (0.63) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL5019074 0.86 LMNA (0.73) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL31662771 0.85 LMNA (0.64) LMNASMN1; SMN2HTTL3MBTL1MAPT
Hydrochloric Acid SCHEMBL4506331 0.84 LMNA (0.71) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL8587051 0.82 LMNA (0.68) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL21338348 0.82 LMNA (0.63) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL14985738 0.82 LMNA (0.63) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL13055383 0.81 LMNA (0.80) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL13898941 0.81 LTA4H (0.50) LMNASMN1; SMN2L3MBTL1ATM
SCHEMBL7364819 0.80 LMNA (0.65) LMNASMN1; SMN2HTTL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS LMNA 3037/4885SMN1; SMN2 1576/4885HTT 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.