Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420909 | 0.86 | LMNA (0.59) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19957925 | 0.85 | HTT (0.59) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL22166825 | 0.84 | HTT (0.68) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL22552974 | 0.84 | HTT (0.54) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL22552975 | 0.84 | HTT (0.54) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL18254066 | 0.83 | HTT (0.81) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL10032568 | 0.83 | HTT (0.67) | HTTLMNASMN1; SMN2L3MBTL1TGM2 | |
| SCHEMBL10845190 | 0.83 | HTT (0.67) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL17108594 | 0.82 | LMNA (0.56) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL17532634 | 0.82 | LMNA (0.79) | HTTLMNASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198278-A1 | SECO MACROLIDE COMPOUNDS | SELVITA D.O.O. (HR) | 2021-07-01 | — | — | US | disclosed |
| US-10919910-B2 | Seco macrolide compounds | FIDELTA D.O.O. (HR) | 2021-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198278-A1 | SECO MACROLIDE COMPOUNDS | SEC61B, SEC16A, SEC61A1 | HTT 1822/4885LMNA 1215/4885SMN1; SMN2 2262/4885 |
| US-10919910-B2 | Seco macrolide compounds | SEC61B, SEC16A, SEC61A1 | HTT 1822/4885LMNA 1215/4885SMN1; SMN2 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.