SCHEMBL31421458

SCHEMBL31421458

N#Cc1cnccc1CCN

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 6/20 0.47
CYP2A6 P11509 6/20 0.47
CYP2E1 P05181 5/20 0.47
CYP2C19 P33261 5/20 0.47
CYP2C8 P10632 4/20 0.47
CYP2B6 P20813 4/20 0.47
CYP2C9 P11712 4/20 0.47
LOXL2 Q9Y4K0 2/20 0.44
HTR6 P50406 1/20 0.44
AOC1 P19801 4/20 0.41
AOC3 Q16853 4/20 0.41
CHRNA7 P36544 1/20 0.40
HTT P42858 1/20 0.40
CYP1A2 P05177 4/20 0.38
CYP3A4 P08684 3/20 0.38
ADRA2C P18825 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
GPR119 Q8TDV5 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6626248 0.81 CYP2E1 (0.59) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL798353 0.81 CYP2E1 (0.41) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL6136913 0.79 CYP2E1 (0.39) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL7219105 0.79 CYP2E1 (0.49) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL6472029 0.77 CYP2E1 (0.48) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL2982329 0.77 HTR6 (0.48) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL11366480 0.77 HTR1A (0.43) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL3280017 0.77 NCOA3 (0.42) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL3822143 0.77 CYP2E1 (0.57) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8
SCHEMBL14825828 0.77 HTT (0.42) CYP2D6CYP2A6CYP2E1CYP2C19CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CYP2D6 2401/4885CYP2A6 3484/4885CYP2E1 2246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.