Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256817 | 0.87 | ULK1 (0.53) | ULK1PSMB8AAK1SCN3ASCN9A | |
| SCHEMBL13256812 | 0.84 | ULK1 (0.53) | ULK1PSMB8AAK1SCN3ASCN9A | |
| SCHEMBL29640005 | 0.82 | KDR (0.57) | ULK1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL850437 | 0.79 | HTT (0.62) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL38659273 | 0.79 | PSMB8 (0.51) | ULK1PSMB8AAK1SCN3ASCN9A | |
| SCHEMBL9892929 | 0.79 | AR (0.49) | ULK1PSMB8 | |
| SCHEMBL31148172 | 0.78 | ULK1 (0.55) | ULK1MEN1KMT2APSMB8EPHX1 | |
| Hydrochloric Acid SCHEMBL31148078 | 0.77 | SCN3A (0.56) | ULK1MEN1KMT2APSMB8EPHX1 | |
| SCHEMBL9892891 | 0.76 | EPHX2 (0.52) | ULK1PSMB8 | |
| Trifluoroacetic Acid SCHEMBL38657934 | 0.76 | PSMB8 (0.48) | ULK1PSMB8AAK1SCN3ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177412-A1 | SMALL-MOLECULE INHIBITORS TARGETING THE BOB1/OCT1 INTERFACE | NANTES UNIVERSITE (FR) | 2025-06-05 | — | — | US | disclosed |
| CN-119585253-A | Small molecule inhibitor targeting BOB1/OCT1 interface | 南特大学 | 2025-03-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177412-A1 | SMALL-MOLECULE INHIBITORS TARGETING THE BOB1/OCT1 INTERFACE | POU2F1, POU5F1, LEF1 | ULK1 4538/4885MAPT 2095/4885MEN1 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.