Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422949 | 0.88 | KDM4E (0.44) | BRD4KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL31273751 | 0.83 | KDM4E (0.44) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL25426199 | 0.77 | MAOB (0.46) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL30529282 | 0.77 | MAOB (0.46) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL5782935 | 0.77 | ATR (0.42) | BRD4KDM4EPAX8NOTUM | |
| SCHEMBL31273624 | 0.75 | KIF11 (0.49) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL18147226 | 0.74 | ALDH1A1 (0.43) | BRD4KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL30485169 | 0.74 | ALDH1A1 (0.43) | BRD4KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL10330638 | 0.73 | KDM4E (0.61) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL24373361 | 0.72 | CHEK1 (0.51) | KDM4EGAAGLAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |