Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422905 | 0.88 | BRD4 (0.39) | KDM4EGAAALDH1A1POLBBRD4 | |
| SCHEMBL31273615 | 0.81 | SLC16A3 (0.54) | KDM4EGAAALDH1A1POLBSLC16A3 | |
| SCHEMBL29276902 | 0.76 | TSHR (0.44) | ALDH1A1POLBBRD4PAX8CREBBP | |
| SCHEMBL25427065 | 0.75 | ALDH1A1 (0.56) | KDM4EGAAALDH1A1POLBSLC16A3 | |
| SCHEMBL30529281 | 0.75 | ALDH1A1 (0.56) | KDM4EGAAALDH1A1POLBSLC16A3 | |
| SCHEMBL2432980 | 0.74 | STAT5B (0.46) | KDM4EGAAALDH1A1POLBBRD4 | |
| SCHEMBL30339105 | 0.74 | RXRB (0.42) | BRD4PAX8CREBBPMEN1KMT2A | |
| SCHEMBL24072766 | 0.74 | RXRB (0.42) | BRD4PAX8CREBBPMEN1KMT2A | |
| SCHEMBL16670002 | 0.73 | KDM4E (0.46) | KDM4EPOLBBRD4PAX8MEN1 | |
| SCHEMBL18147237 | 0.73 | ALDH1A1 (0.44) | KDM4EGAAALDH1A1POLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |