Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423302 | 0.99 | MMP9 (0.36) | ACMSDPOLBTHRBKDM4EHSD17B10 | |
| SCHEMBL31273321 | 0.97 | MMP9 (0.38) | ACMSDPOLBTHRBKDM4EHSD17B10 | |
| SCHEMBL31273371 | 0.94 | DAO (0.37) | POLBKDM4EHSD17B10MMP9DAO | |
| SCHEMBL31422953 | 0.83 | DAO (0.35) | POLBKDM4EHSD17B10DAODDO | |
| SCHEMBL31422768 | 0.82 | MAOB (0.53) | POLBKDM4EHSD17B10MAOBMAOA | |
| SCHEMBL31273396 | 0.82 | KDM4E (0.42) | POLBKDM4EHSD17B10MMP9ALDH1A1 | |
| SCHEMBL31423089 | 0.81 | MAOB (0.51) | POLBKDM4EHSD17B10MAOBMAOA | |
| SCHEMBL31423183 | 0.80 | ACMSD (0.54) | ACMSDPOLBKDM4EHSD17B10MMP9 | |
| SCHEMBL31273200 | 0.79 | DAO (0.55) | KDM4EHSD17B10DAODDOALDH1A1 | |
| SCHEMBL29479161 | 0.79 | KDM4E (0.44) | POLBKDM4EHSD17B10MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |