Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423121 | 0.89 | TP53 (0.39) | ALDH1A1SMN1; SMN2KDM4EHPGDADORA3 | |
| SCHEMBL31423001 | 0.87 | ADORA3 (0.37) | ALDH1A1KDM4EHPGDADORA3GAA | |
| SCHEMBL31423077 | 0.87 | KDM4E (0.35) | ALDH1A1SMN1; SMN2KDM4EHPGDADORA3 | |
| SCHEMBL31423157 | 0.81 | NPC1 (0.43) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL31423303 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL31422777 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL21917 | 0.79 | TSHR (0.50) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL31422974 | 0.79 | RAB9A (0.41) | ALDH1A1SMN1; SMN2KDM4EADORA3POLB | |
| SCHEMBL31423006 | 0.78 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL31422855 | 0.78 | KDM4E (0.40) | ALDH1A1KDM4EHPGDTBK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |