Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 12/20 | 0.66 |
| ▸ | WDR48 | Q8TAF3 | 9/20 | 0.66 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.57 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423492 | 0.85 | USP1 (0.65) | USP1WDR48PIP4K2CCETP | |
| SCHEMBL31423616 | 0.84 | TRPM8 (0.64) | USP1WDR48TRPM8PIP4K2CMITF | |
| SCHEMBL31423499 | 0.82 | USP1 (0.48) | USP1WDR48MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30462019 | 0.81 | TRPM8 (0.57) | USP1WDR48TRPM8F10LMNA | |
| SCHEMBL26627858 | 0.81 | TRPM8 (0.57) | USP1WDR48TRPM8F10LMNA | |
| SCHEMBL31423693 | 0.81 | USP1 (0.55) | USP1WDR48TRPM8 | |
| SCHEMBL31423569 | 0.74 | USP1 (0.51) | USP1WDR48TRPM8 | |
| SCHEMBL1442185 | 0.74 | TRPM8 (1.00) | TRPM8MITFLMNAMAPTSMN1; SMN2 | |
| SCHEMBL31423668 | 0.73 | USP1 (0.54) | USP1WDR48TRPM8 | |
| SCHEMBL30462090 | 0.72 | USP1 (0.58) | USP1WDR48TRPM8PIP4K2CMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741386-A1 | PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2026-05-13 | — | — | EP | disclosed |
| EP-4516779-A1 | PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-03-05 | — | — | EP | disclosed |