Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | AMD1 | P17707 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25385595 | 0.82 | JAK2 (0.39) | JAK2PIK3CDPIK3CGNUDT1MAPT | |
| SCHEMBL31489346 | 0.77 | JAK2 (0.48) | JAK2PIK3CDPIK3CGNUDT1HSP90AA1 | |
| SCHEMBL18952793 | 0.76 | JAK1 (0.33) | ADORA2AALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL18952580 | 0.75 | JAK2 (0.52) | JAK2ADORA2APIK3CDPIK3CGNUDT1 | |
| Trifluoroacetic Acid SCHEMBL31489607 | 0.74 | JAK2 (0.39) | JAK2PIK3CDPIK3CGMAPTHSD17B10 | |
| SCHEMBL31424000 | 0.74 | JAK2 (0.34) | JAK2NUDT1ALDH1A1MAPTKDM4E | |
| SCHEMBL31489350 | 0.71 | JAK2 (0.41) | JAK2ADORA2APIK3CDPIK3CGNUDT1 | |
| SCHEMBL31586363 | 0.70 | JAK2 (0.34) | JAK2NUDT1KMT2A | |
| SCHEMBL18615048 | 0.69 | JAK2 (0.69) | JAK2NUDT1ALDH1A1KDM4ESCN9A | |
| SCHEMBL31423940 | 0.69 | JAK2 (0.38) | JAK2PIK3CDPIK3CGSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096061-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025054386-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |