Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489346 | 0.87 | JAK2 (0.48) | JAK2PDGFRBKDRPIK3CDPIK3CG | |
| Trifluoroacetic Acid SCHEMBL31489306 | 0.84 | JAK2 (0.38) | JAK2MAPT | |
| SCHEMBL31423910 | 0.74 | JAK2 (0.41) | JAK2HSD17B10MAPTSMN1; SMN2TSHR | |
| SCHEMBL25385595 | 0.72 | JAK2 (0.39) | JAK2HSD17B10DHFRMAPTSMN1; SMN2 | |
| SCHEMBL23209564 | 0.70 | JAK2 (0.48) | JAK2HSD17B10PKMMAPTPIK3CD | |
| SCHEMBL31489350 | 0.68 | JAK2 (0.41) | JAK2PIK3CDPIK3CG | |
| SCHEMBL23761335 | 0.68 | JAK2 (0.41) | JAK2PIK3CDPIK3CG | |
| SCHEMBL31586363 | 0.67 | JAK2 (0.34) | JAK2 | |
| SCHEMBL31489508 | 0.66 | KDM4E (0.36) | — | |
| SCHEMBL31480915 | 0.65 | NUDT1 (0.49) | JAK2PIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |