Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31489607 | 0.87 | JAK2 (0.39) | JAK2PIK3CDPIK3CGPDGFRBKDR | |
| SCHEMBL25385595 | 0.83 | JAK2 (0.39) | JAK2NUDT1PIK3CDPIK3CGPDGFRB | |
| SCHEMBL23209564 | 0.81 | JAK2 (0.48) | JAK2NUDT1PIK3CDPIK3CGPIK3CB | |
| SCHEMBL23761335 | 0.78 | JAK2 (0.41) | JAK2NUDT1PIK3CDPIK3CGPIK3CB | |
| SCHEMBL31423910 | 0.77 | JAK2 (0.41) | JAK2NUDT1PIK3CDPIK3CGHSP90AB1 | |
| SCHEMBL31586363 | 0.77 | JAK2 (0.34) | JAK2NUDT1 | |
| SCHEMBL31489508 | 0.76 | KDM4E (0.36) | NQO2 | |
| SCHEMBL31489350 | 0.75 | JAK2 (0.41) | JAK2NUDT1PIK3CDPIK3CGPIK3CB | |
| SCHEMBL31480915 | 0.75 | NUDT1 (0.49) | JAK2NUDT1PIK3CDPIK3CGPIK3CB | |
| SCHEMBL31489886 | 0.72 | JAK2 (0.40) | JAK2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |