Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23761335 | 0.82 | JAK2 (0.41) | JAK2NUDT1PDE10APIK3CDPIK3CG | |
| SCHEMBL31480915 | 0.79 | NUDT1 (0.49) | JAK2NUDT1PDE10APIK3CDPIK3CG | |
| SCHEMBL25439983 | 0.79 | JAK2 (0.41) | JAK2NUDT1PIK3CDPIK3CGPIK3CB | |
| SCHEMBL1810011 | 0.76 | JAK2 (0.56) | JAK2NUDT1PDE10APIK3CDPIK3CG | |
| SCHEMBL31489346 | 0.75 | JAK2 (0.48) | JAK2NUDT1PIK3CDPIK3CGPIK3CB | |
| SCHEMBL25440007 | 0.75 | JAK2 (0.38) | JAK2NUDT1PIK3CDPIK3CGPIK3CB | |
| Trifluoroacetic Acid SCHEMBL31489306 | 0.74 | JAK2 (0.38) | JAK2NUDT1PDE10AADORA3ADORA2A | |
| SCHEMBL31423910 | 0.71 | JAK2 (0.41) | JAK2NUDT1PIK3CDPIK3CGADORA2A | |
| SCHEMBL31489851 | 0.71 | PIK3CD (0.33) | JAK2PIK3CDPIK3CGPIK3CB | |
| SCHEMBL25385595 | 0.71 | JAK2 (0.39) | JAK2NUDT1PIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |