Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24276775 | 0.85 | USP30 (0.33) | NR1H2NR1H3ACACBLMNANPSR1 | |
| SCHEMBL31692233 | 0.81 | NPSR1 (0.35) | NR1H2NR1H3ACACBLMNANPSR1 | |
| SCHEMBL24276764 | 0.77 | MAP4K4 (0.33) | NR1H2NR1H3ACACBLMNANPSR1 | |
| SCHEMBL35212552 | 0.75 | TLR9 (0.34) | NR1H2NR1H3LMNA | |
| SCHEMBL24276770 | 0.73 | GRM5 (0.36) | NR1H2NR1H3ACACBLMNANPSR1 | |
| SCHEMBL34466888 | 0.73 | UCHL1 (0.33) | NR1H2NR1H3LMNANPSR1USP30 | |
| SCHEMBL34465741 | 0.73 | UCHL1 (0.33) | NR1H2NR1H3LMNANPSR1USP30 | |
| SCHEMBL31692539 | 0.72 | KAT7 (0.35) | NR1H2NR1H3LMNANPSR1GPR119 | |
| SCHEMBL24276763 | 0.70 | LMNA (0.30) | LMNANPSR1 | |
| SCHEMBL26185733 | 0.70 | KAT7 (0.34) | NR1H2NR1H3LMNANPSR1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431365-A | Phenyl heterocyclic derivative-containing regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-02-14 | — | — | CN | disclosed |