Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 9/20 | 0.55 |
| ▸ | MMP2 | P08253 | 6/20 | 0.55 |
| ▸ | MMP14 | P50281 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424332 | 1.00 | MMP13 (0.55) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL31424367 | 0.82 | KDM4E (0.45) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL23749652 | 0.81 | MMP13 (0.57) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL30216943 | 0.81 | MMP13 (0.57) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL31472052 | 0.77 | ALDH1A1 (0.38) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL16306719 | 0.75 | MMP13 (0.58) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL419130 | 0.74 | MMP13 (0.77) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL3500194 | 0.73 | MMP13 (0.75) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL25024764 | 0.72 | MMP13 (0.78) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL31619711 | 0.72 | KDM4E (0.58) | MMP13MMP2MMP14KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431365-A | Phenyl heterocyclic derivative-containing regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-02-14 | — | — | CN | disclosed |