Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424804 | 0.88 | DHODH (0.41) | L3MBTL1TP53POLBRAB9ACHEK1 | |
| SCHEMBL31424711 | 0.87 | KMT2A (0.41) | KMT2AKDM4EALDH1A1CDK5CDK5R1 | |
| SCHEMBL31424753 | 0.87 | ADORA3 (0.41) | KDM4EALDH1A1GRIN1GRIN2B | |
| SCHEMBL31424600 | 0.85 | SLC2A1 (0.39) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL31424846 | 0.85 | ALDH1A1 (0.44) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL31424818 | 0.84 | DHODH (0.37) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31424706 | 0.80 | MAPK1 (0.40) | CHEK1MAPK1 | |
| SCHEMBL30979307 | 0.79 | GRIN2D (0.36) | POLBKDM4EALDH1A1HTTGRIN2D | |
| SCHEMBL30979321 | 0.78 | GRIN2D (0.35) | KDM4EALDH1A1HTTTDP1RXFP1 | |
| SCHEMBL30979299 | 0.77 | PARP1 (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020129-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-05-20 | — | — | CN | disclosed |
| CN-119431314-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |