Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424805 | 0.89 | GRIN2D (0.45) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL31424600 | 0.88 | SLC2A1 (0.39) | ALDH1A1LMNAADORA1KDM4E | |
| SCHEMBL31424840 | 0.85 | L3MBTL1 (0.40) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31424753 | 0.84 | ADORA3 (0.41) | ALDH1A1LMNAGRIN1GRIN2BDHODH | |
| SCHEMBL31424711 | 0.80 | KMT2A (0.41) | ALDH1A1DHODHPIM1CDK5KDM4E | |
| SCHEMBL31424727 | 0.80 | NEK1 (0.45) | ALDH1A1LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31424798 | 0.80 | NEK1 (0.45) | ALDH1A1LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31424624 | 0.77 | SLC2A1 (0.40) | ALDH1A1ADORA1KDM4E | |
| SCHEMBL31424693 | 0.75 | GRIN1 (0.37) | GRIN1GRIN2BDHODH | |
| SCHEMBL31424818 | 0.75 | DHODH (0.37) | ALDH1A1DHODHADORA2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431314-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |