Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | BRD1 | O95696 | 2/20 | 0.35 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471279 | 0.85 | BRD4 (0.41) | BRPF1QDPRBRD1BRPF3ALDH1A1 | |
| SCHEMBL26111817 | 0.85 | BRD4 (0.41) | BRPF1QDPRBRD1BRPF3ALDH1A1 | |
| SCHEMBL31425919 | 0.83 | MAPK14 (0.38) | BRPF1QDPRBRD1BRPF3NPC1 | |
| SCHEMBL31425891 | 0.80 | ADAM17 (0.44) | QDPRPDE4BKDM4E | |
| SCHEMBL31425931 | 0.78 | PDE4B (0.48) | QDPRPDE4BKDM4EALDH1A1HPGD | |
| SCHEMBL31426008 | 0.77 | LMNA (0.40) | TLR9TLR7TLR8QDPRKDM4E | |
| SCHEMBL31426281 | 0.75 | HTR2C (0.42) | BRPF1HTR2CTLR9TLR7TLR8 | |
| SCHEMBL31425866 | 0.73 | BRD1 (0.34) | BRPF1BRD1BRPF3KDM4EALDH1A1 | |
| SCHEMBL29471200 | 0.72 | MEN1 (0.43) | BRPF1BRD1BRPF3KDM4EALDH1A1 | |
| SCHEMBL26547628 | 0.72 | MEN1 (0.43) | BRPF1BRD1BRPF3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250114345-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS | 2025-04-10 | — | — | US | disclosed |
| WO-2025049994-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) | 2025-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250114345-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | EP300, CREBBP, HDAC1 | BRPF1 221/4885HTR2C 3500/4885TLR9 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.