SCHEMBL29471200

SCHEMBL29471200

COc1cc(Br)cc2c1cc(C)c(=O)n2C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ LMNA P02545 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ BRD4 O60885 4/20 0.40
▸ BRD2 P25440 2/20 0.40
▸ BRD9 Q9H8M2 2/20 0.40
▸ BRD7 Q9NPI1 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ CYP19A1 P11511 4/20 0.39
▸ NQO2 P16083 4/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ BRPF1 P55201 5/20 0.38
▸ BRD1 O95696 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26547628 1.00 MEN1 (0.43) MEN1KMT2AL3MBTL1LMNATSHR
SCHEMBL26547742 0.80 BRPF1 (0.40) MEN1KMT2AL3MBTL1LMNATSHR
SCHEMBL31248987 0.79 PTGS2 (0.42) MEN1KMT2AL3MBTL1LMNABRD4
SCHEMBL30993671 0.79 BRD4 (0.39) MEN1KMT2AL3MBTL1BRD4BRD2
SCHEMBL31248925 0.78 TTR (0.40) MEN1KMT2AL3MBTL1BRD4BRD2
SCHEMBL31248669 0.78 LMNA (0.46) MEN1KMT2AL3MBTL1LMNATSHR
SCHEMBL30993226 0.77 BRD4 (0.37) MEN1KMT2AL3MBTL1LMNATSHR
SCHEMBL31248776 0.77 BRD4 (0.37) MEN1KMT2AL3MBTL1BRD4BRD2
SCHEMBL26547632 0.76 CYP19A1 (0.43) MEN1KMT2AL3MBTL1LMNATSHR
SCHEMBL31426151 0.76 NQO2 (0.53) MEN1KMT2AL3MBTL1TSHRBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. 2025-05-01 — — US disclosed
WO-2025081092-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. (US) 2025-04-17 — — WO disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed
EP-4210683-A1 HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS Aurigene Oncology Limited (IN) 2023-07-19 — — EP disclosed
CN-116368128-A Heterocyclic compounds as CBP/EP300 bromodomain inhibitors 奥瑞基尼肿瘤有限公司 2023-06-30 — — CN disclosed
WO-2022053967-A1 HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2022-03-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS AR, SHBG, FSHR MEN1 1342/4885KMT2A 1474/4885L3MBTL1 4522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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