Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428510 | 0.82 | FKBP1A (0.65) | FKBP1ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL24977050 | 0.81 | ALDH1A1 (0.60) | FKBP1ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL31428972 | 0.81 | ALDH1A1 (0.60) | FKBP1ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL5064530 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2POLBALDH1A1KCNH2MAPT | |
| SCHEMBL31428940 | 0.79 | FKBP1A (0.56) | FKBP1ASMN1; SMN2NPC1ALDH1A1KCNH2 | |
| SCHEMBL7978731 | 0.76 | PTPN7 (0.66) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL6984876 | 0.76 | MKNK1 (0.62) | SMN1; SMN2HPGD | |
| SCHEMBL31428914 | 0.76 | FKBP1A (0.61) | FKBP1ASMN1; SMN2HPGDPOLBKEAP1 | |
| SCHEMBL1101337 | 0.76 | KDM4E (0.68) | FKBP1ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL12606385 | 0.76 | RIPK1 (0.51) | FKBP1ASMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | FKBP1A 2064/4885SMN1; SMN2 4832/4885HPGD 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.